Browsing by Author "Ozdemir, Ercan"
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Attenuation of morphine antinociceptive tolerance by cannabinoid CB1 and CB2 receptor antagonists
Altun, Ahmet; Yildirim, Kemal; Ozdemir, Ercan; Bagcivan, Ihsan; Gursoy, Sinan; Durmus, Nedim (SPRINGER JAPAN KK, 2015)Cannabinoid CB1 and CB2 receptor antagonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of opioid tolerance. The aim of this study was to investigate the ... -
Comparison of Analgesic Effects Induced by Different Strengths of Extremely Low-Frequency Electromagnetic Fields
Demirkazik, Ayse; Ozdemir, Ercan; Turkay, Yavuz; Pelit, Aykut; Kilinc, Olca; Taskiran, Ahmet Sevki; Arslan, Gokhan (AVES PRESS LTD, 2018)Objective: Our aim was to compare the results of the most commonly used analgesic measurement techniques and to determine the time and intensity at which the analgesic effects of the magnetic field (MF) are most effective. ... -
Effect of cervical spinal cord electrical stimulation on nitric oxide levels in brain and dermal tissues: an evaluation using by real-time nitric oxide measurement
Ozum, Unal; Akyol, Melih; Balaban, Hatice; Ozdemir, Ercan; Soydan, Serdar (SPRINGER WIEN, 2012)Nitric oxide synthesized from L-arginine via the nitric oxide synthase enzyme family is the main regulatory molecule in many physiological systems. The level of nitric oxide can now be measured in tissues by a direct ... -
Effect of the allopregnanolone and allotetrahydrodeoxycorticosteron on spike-wave discharges in the EEG of absence epilepsy rat models
Karabulut, Sebahattin; Bayramov, Ruslan; Bayramov, Keziban Korkmaz; Filiz, Ahmet K.; Taskiran, Ahmet S.; Ozdemir, Ercan (GENERAL PHYSIOL AND BIOPHYSICS, 2018)Absence epilepsy is a generalized nonconvulsive type of epilepsy that is characterized by spike-wave discharges (SWD) with a frequency of 2.5-4 Hz in the EEG. The activation of the GABAergic system in central nervous system ... -
Effects of 5-HT1 and 5-HT2 Receptor Agonists on Electromagnetic Field-Induced Analgesia in Rats
Ozdemir, Ercan; Demirkazik, Ayse; Taskiran, Ahmet Sevki; Arslan, Gokhan (WILEY, 2019)Much evidence demonstrates the antinociceptive effect of magnetic fields (MFs). However, the analgesic action mechanism of the electromagnetic field (EMF) is not exactly understood. The aim of the present study was to ... -
Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats
Gursoy, Sinan; Ozdemir, Ercan; Bagcivan, Ihsan; Altun, Ahmet; Durmus, Nedim (TAYLOR & FRANCIS LTD, 2011)Background. Alpha 2 (alpha(2))-adrenoceptor agonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of opioid tolerance. The purpose of this study was to investigate ... -
The effects of creatine long-term supplementation on muscle morphology and swimming performance in rats
Yildiz, Ahmet; Ozdemir, Ercan; Gulturk, Sefa; Erdal, Sena (JOURNAL SPORTS SCIENCE & MEDICINE, 2009)Creatine (Cr) has been shown to increase the total muscle mass. The purpose of this study was to investigate the effect of Cr supplementation on muscle morphology and swimming performance, using an animal model. Each rat ... -
The effects of endocannabinoid receptor agonist anandamide and antagonist rimonabant on opioid analgesia and tolerance in rats
Altun, Ahmet; Ozdemir, Ercan; Yildirim, Kemal; Gursoy, Sinan; Durmus, Nedim; Bagcivan, Ihsan (GENERAL PHYSIOL AND BIOPHYSICS, 2015)The role of the cannabinoid (CB) system in the tolerance to analgesic effect of opioid remains obscure. The aim of the present study was to evaluate the effects of the endocannabinoid nonselective receptor agonist anandamide ... -
Effects of extremely low frequency electromagnetic fields on morphine analgesia and tolerance in rats
Ozdemir, Ercan; Demirkazik, Ayse; Gursoy, Sinan; Taskiran, Ahmet S.; Kilinc, Olca; Arslan, Gokhan (GENERAL PHYSIOL AND BIOPHYSICS, 2017)Several studies have demonstrated that the electromagnetic fields produce analgesic activity. The aim of this study was to investigate the effects of extremely low frequency (ELF) electromagnetic fields (EMF) on morphine ... -
The effects of serotonin/norepinephrine reuptake inhibitors and serotonin receptor agonist on morphine analgesia and tolerance in rats
Ozdemir, Ercan; Gursoy, Sinan; Bagcivan, Ihsan (SPRINGER TOKYO, 2012)Several studies have demonstrated that serotonergic and noradrenergic systems have important roles in morphine analgesia and tolerance. However, the exact mechanism underlying the development of morphine tolerance is not ...